Loading required namespace: GenomicFiles Using local VCF. File already tabix-indexed. Finding empty VCF columns based on first 10,000 rows. Dropping 1 duplicate column(s). 1 sample detected: EBI-a-GCST005898 Constructing ScanVcfParam object. VCF contains: 417,240 variant(s) x 1 sample(s) Reading VCF file: multi-threaded (4 threads) Timing stopped at: 0.528 0.39 0.386 BiocParallel errors 4 remote errors, element index: 1, 2, 3, 4 0 unevaluated and other errors first remote error: Error: scanVcf: scanVcf: scanTabix: '1' not present in tabix index path: /rds/general/project/neurogenomics-lab/ephemeral/MAGMA_Files_Public/data/VCFs/ebi-a-GCST005898.vcf.gz index: /rds/general/project/neurogenomics-lab/ephemeral/MAGMA_Files_Public/data/VCFs/ebi-a-GCST005898.vcf.gz.tbi path: /rds/general/project/neurogenomics-lab/ephemeral/MAGMA_Files_Public/data/VCFs/ebi-a-GCST005898.vcf.gz Done with all processing in 0.11 minutes. ===================== 🦠🌋🦠 Welcome to MAGMA.Celltyping 🦠🌋🦠 ===================== This package uses MAGMA: https://ctg.cncr.nl/software/magma To cite MAGMA.Celltyping, please use: * Skene, N.G., Bryois, J., Bakken, T.E. et al. Genetic identification of brain cell types underlying schizophrenia. Nat Genet 50, 825-833 (2018). https://doi.org/10.1038/s41588-018-0129-5 * de Leeuw CA, Mooij JM, Heskes T, Posthuma D (2015) MAGMA: Generalized Gene-Set Analysis of GWAS Data. PLOS Computational Biology 11(4): e1004219. https://doi.org/10.1371/journal.pcbi.1004219 Please report any bugs or feature requests by filling out an Issues template: https://github.com/neurogenomics/MAGMA_Celltyping/issues ===================== 🦠🌋🦠 =========================== 🦠🌋🦠 ===================== Installed MAGMA version: v1.10 Skipping MAGMA installation. The desired_version of MAGMA is currently installed: v1.10 Using: magma_v1.10 Using existing genome_ref found in storage_dir. Error in path.expand(x) : invalid 'path' argument Calls: lapply -> FUN -> -> fix_path -> path.expand Execution halted Loading required namespace: GenomicFiles Using local VCF. File already tabix-indexed. Finding empty VCF columns based on first 10,000 rows. Dropping 1 duplicate column(s). 1 sample detected: EBI-a-GCST005898 Constructing ScanVcfParam object. VCF contains: 417,240 variant(s) x 1 sample(s) Reading VCF file: multi-threaded (4 threads) Timing stopped at: 0.584 0.395 0.403 BiocParallel errors 4 remote errors, element index: 1, 2, 3, 4 0 unevaluated and other errors first remote error: Error: scanVcf: scanVcf: scanTabix: '1' not present in tabix index path: /rds/general/project/neurogenomics-lab/ephemeral/MAGMA_Files_Public/data/VCFs/ebi-a-GCST005898.vcf.gz index: /rds/general/project/neurogenomics-lab/ephemeral/MAGMA_Files_Public/data/VCFs/ebi-a-GCST005898.vcf.gz.tbi path: /rds/general/project/neurogenomics-lab/ephemeral/MAGMA_Files_Public/data/VCFs/ebi-a-GCST005898.vcf.gz Done with all processing in 0.1 minutes. Registered S3 methods overwritten by 'treeio': method from MRCA.phylo tidytree MRCA.treedata tidytree Nnode.treedata tidytree Ntip.treedata tidytree ancestor.phylo tidytree ancestor.treedata tidytree child.phylo tidytree child.treedata tidytree full_join.phylo tidytree full_join.treedata tidytree groupClade.phylo tidytree groupClade.treedata tidytree groupOTU.phylo tidytree groupOTU.treedata tidytree is.rooted.treedata tidytree nodeid.phylo tidytree nodeid.treedata tidytree nodelab.phylo tidytree nodelab.treedata tidytree offspring.phylo tidytree offspring.treedata tidytree parent.phylo tidytree parent.treedata tidytree root.treedata tidytree rootnode.phylo tidytree sibling.phylo tidytree ===================== 🦠🌋🦠 Welcome to MAGMA.Celltyping 🦠🌋🦠 ===================== This package uses MAGMA: https://ctg.cncr.nl/software/magma To cite MAGMA.Celltyping, please use: * Skene, N.G., Bryois, J., Bakken, T.E. et al. Genetic identification of brain cell types underlying schizophrenia. Nat Genet 50, 825-833 (2018). https://doi.org/10.1038/s41588-018-0129-5 * de Leeuw CA, Mooij JM, Heskes T, Posthuma D (2015) MAGMA: Generalized Gene-Set Analysis of GWAS Data. PLOS Computational Biology 11(4): e1004219. https://doi.org/10.1371/journal.pcbi.1004219 Please report any bugs or feature requests by filling out an Issues template: https://github.com/neurogenomics/MAGMA_Celltyping/issues ===================== 🦠🌋🦠 =========================== 🦠🌋🦠 ===================== Installed MAGMA version: v1.10 Skipping MAGMA installation. The desired_version of MAGMA is currently installed: v1.10 Using: magma_v1.10 genome_ref not found in storage_dir. Downloading from remote server instead ==> /rds/general/project/neurogenomics-lab/ephemeral/magma_storage.20f09b25c2ce8c/g1000_eur Unzipping file. Error in path.expand(x) : invalid 'path' argument Calls: lapply -> FUN -> -> fix_path -> path.expand In addition: Warning messages: 1: In utils::download.file(url = input_url, destfile = zipfile) : URL https://ctg.cncr.nl/software/MAGMA/ref_data/g1000_eur.zip: cannot open destfile '/rds/general/project/neurogenomics-lab/ephemeral/magma_storage.20f09b25c2ce8c/g1000_eur.zip', reason 'No such file or directory' 2: In utils::download.file(url = input_url, destfile = zipfile) : download had nonzero exit status 3: In utils::unzip(zipfile = zipfile, exdir = genome_ref_dir, overwrite = TRUE) : error 1 in extracting from zip file Execution halted